Milbemycin A4 oxime
Milbemycin A4 oxime is a bioactive derivative with insecticidal and nematocidal properties. It demonstrates efficacy against canine heartworm microfilariae in vivo and exhibits in vitro antifungal activity by inhibiting efflux pumps in Candida glabrata, thereby potentiating azole drugs. Furthermore, it reverses multidrug resistance in cancer cells by blocking P-glycoprotein efflux transporters.
Product Specifications
CAS Number
93074-04-5
Field of Research
Infectious Disease & Virology
Smiles
CC[C@H]1O[C@]2 (CC[C@@H]1C) C[C@@H]1C[C@@H] (C\C=C (C) \C[C@@H] (C) \C=C\C=C3/CO[C@@H]4\C (=N/O) C (C) =C[C@@H] (C (=O) O1) [C@]34O) O2
Molecular Formula
C32H45NO7
Molecular Weight
555.712
Storage Conditions
-20°C
Notes
For research use only.
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