O-11
O-11 is a myristic acid analog where oxygen replaces the methylene at carbon 11. It potently and selectively kills Trypanosoma brucei (LD50 <1 μM) by inhibiting myristate incorporation into the VSG GPI anchor, disrupting immune evasion. It shows minimal anti-fungal activity but minor inhibition of HIV-1 replication in T-cells.
Product Specifications
CAS Number
119290-12-9
Field of Research
Infectious Disease & Virology
Smiles
C (CCCCOCCC) CCCCC (O) =O
Molecular Formula
C13H26O3
Molecular Weight
230.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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