Paraherquamide A
Paraherquamide A is a potent mycotoxin-derived anthelmintic that acts as a nanomolar antagonist of acetylcholine receptors. It demonstrates efficacy in vitro against C. elegans and in vivo against nematode infections in gerbils, though it exhibits toxicity in murine models. This compound is a valuable research tool for studying nicotinic acetylcholine receptor function and anthelmintic mechanisms.
Product Specifications
CAS Number
77392-58-6
Smiles
CN1C (=O) [C@]23C[C@H]4C (C) (C) [C@@]5 (C[C@]14CN2CC[C@@]3 (C) O) C (=O) Nc1c5ccc2OC (C) (C) C=COc12
Molecular Formula
C28H35N3O5
Molecular Weight
493.604
Storage Conditions
-20°C
Notes
For research use only.
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