Simotinib
Simotinib (AL-6802) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 19.9 nM. It demonstrates anti-tumor activity in non-small cell lung cancer (NSCLC) research, showing efficacy in both in vitro cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
944258-89-3
Product Name Alternative
Simotinib, SIM-6802, AL-6802, EGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.70% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2 mM) ; DMSO:10 mg/mL (19.96 mM)
Smiles
COc1cc2ncnc (Nc3ccc (F) c (Cl) c3) c2cc1OCCN1CC2 (CC2) C2 (C1) OCCO2
Molecular Formula
C25H26ClFN4O4
Molecular Weight
500.95
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6440090-01 0.1 mL
TBXAS1 (Thromboxane A Synthase 1, TS, TXS, CYP5, THAS, TXAS, CYP5A1, GHOSAL, BDPLT14) (MaxLight 750)
Sign In for Pricing
View Details MBS6440090-02 5x 0.1 mL
TBXAS1 (Thromboxane A Synthase 1, TS, TXS, CYP5, THAS, TXAS, CYP5A1, GHOSAL, BDPLT14) (MaxLight 750)
Sign In for Pricing
View Details 
231108-01 25 mg
(2R,3R) -3-Amino-2-hydroxy-3-phenylpropionic acid 98+% (TLC)
Sign In for Pricing
View Details 231108-02 100 mg
(2R,3R) -3-Amino-2-hydroxy-3-phenylpropionic acid 98+% (TLC)
Sign In for Pricing
View Details 231108-03 250 mg
(2R,3R) -3-Amino-2-hydroxy-3-phenylpropionic acid 98+% (TLC)
Sign In for Pricing
View Details