P38 MAPK Inhibitor
This small molecule p38 MAPK inhibitor exhibits potent activity with an IC50 of 35 nM. It effectively suppresses oncogenic RAS-induced senescence, making it a valuable tool for studying cellular aging, stress signaling, and cancer biology in both in vitro and in vivo models.
Product Specifications
CAS Number
219138-24-6
Product Name Alternative
P38 MAPK Inhibitor, p-38 MAPK Inhibitor, p38 MAPK, p38MAPK
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.24% (May vary between batches)
Solubility
DMSO:10 mg/mL (27.34 mM) ; Ethanol:0.3 mg/mL (0.82 mM) ; DMF:5 mg/mL (13.67 mM) ; DMSO:PBS (pH7.2) (1:1) :0.5 mg/mL (1.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.73 mM)
Smiles
O=C1C (=C (NN1C2=CC=C (Cl) C=C2) C=3C=CN=CC3) C4=CC=C (F) C=C4
Molecular Formula
C20H13ClFN3O
Molecular Weight
365.79
Storage Conditions
-20°C
Notes
For research use only.
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