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Cysmethynil

Cysmethynil is a time-dependent, indole-based inhibitor of Icmt, disrupting RAS membrane localization and EGF signaling. It induces G1 cell cycle arrest and autophagy, demonstrating antitumor activity in research models. This compound is utilized for studying oncogenic pathways and potential therapeutic interventions in solid tumors.

Product Specifications

CAS Number

851636-83-4

Product Name Alternative

Cysmethynil, Autophagy, isoprenylcysteine carboxylmethyltransferase (ICMT), Ras

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.00% (May vary between batches)

Solubility

DMSO:2 mg/mL (5.31 mM) ; Ethanol:20 mg/mL (53.12 mM) ; DMF:3.3 mg/mL (8.76 mM)

Smiles

O=C (N) CC1=CN (C2=CC=C (C=C21) C=3C=CC=C (C3) C) CCCCCCCC

Molecular Formula

C25H32N2O

Molecular Weight

376.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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