RMC-5552
RMC-5552 is a highly selective mTORC1 inhibitor with low nM potency against pS6K and p4EBP1, demonstrating ~40-fold selectivity over mTORC2. This tool compound is valuable for mTOR pathway research and has shown promising anticancer activity in preclinical in vitro and in vivo studies.
Product Specifications
CAS Number
2382768-62-7
Product Name Alternative
RMC5552, RMC 5552
Field of Research
Signal Transduction
Purity
99.75% (May vary between batches)
Solubility
DMSO:≥ 80 mg/mL
Smiles
[H][C@@]12CC[C@@H] (C) [C@@] (O) (O1) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@] ([H]) (C[C@@H] (O) [C@H] (C) \C=C (C) \[C@@H] (O) [C@@H] (OC) C (=O) [C@H] (C) C[C@H] (C) \C=C\C=C\C=C (C) \[C@H] (C2) OC) [C@H] (C) C[C@@H]1CC[C@@H] (OC (=O) NCCOCCOCCOCCOCCOCCOCCOCCOCCC (=O) N2CCc3cc (Cn4nc (-c5ccc6oc (N) nc6c5) c5c (N) ncnc45) ccc3C2) [C@@H] (C1) OC
Molecular Formula
C93H136N10O24
Molecular Weight
1778.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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