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RMC-5552

RMC-5552 is a highly selective mTORC1 inhibitor with low nM potency against pS6K and p4EBP1, demonstrating ~40-fold selectivity over mTORC2. This tool compound is valuable for mTOR pathway research and has shown promising anticancer activity in preclinical in vitro and in vivo studies.

Product Specifications

CAS Number

2382768-62-7

Product Name Alternative

RMC5552, RMC 5552

Field of Research

Signal Transduction

Purity

99.75% (May vary between batches)

Solubility

DMSO:≥ 80 mg/mL

Smiles

[H][C@@]12CC[C@@H] (C) [C@@] (O) (O1) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@] ([H]) (C[C@@H] (O) [C@H] (C) \C=C (C) \[C@@H] (O) [C@@H] (OC) C (=O) [C@H] (C) C[C@H] (C) \C=C\C=C\C=C (C) \[C@H] (C2) OC) [C@H] (C) C[C@@H]1CC[C@@H] (OC (=O) NCCOCCOCCOCCOCCOCCOCCOCCOCCC (=O) N2CCc3cc (Cn4nc (-c5ccc6oc (N) nc6c5) c5c (N) ncnc45) ccc3C2) [C@@H] (C1) OC

Molecular Formula

C93H136N10O24

Molecular Weight

1778.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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