Thiocoraline
Thiocoraline is a depsipeptide antibiotic and DNA bis-intercalator with potent activity against Gram-positive bacteria and various cancer cell lines. It inhibits key enzymes like DNA/RNA polymerases and thymidylate synthase, disrupting nucleic acid synthesis in vitro, making it a valuable tool for anticancer and antimicrobial mechanism studies.
Product Specifications
CAS Number
173046-02-1
Field of Research
Infectious Disease & Virology
Smiles
CSCC1N (C) C (=O) C2CSSCC (N (C) C (=O) CNC (=O) C (CSC1=O) NC (=O) c1nc3ccccc3cc1O) C (=O) N (C) C (CSC) C (=O) SCC (NC (=O) c1nc3ccccc3cc1O) C (=O) NCC (=O) N2C
Molecular Formula
C48H56N10O12S6
Molecular Weight
1157.39
Storage Conditions
-20°C
Notes
For research use only.
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