TNF-α-IN-2
TNF-α-IN-2 is a potent, orally bioavailable small molecule that disrupts TNFα trimerization and subsequent TNFR1 signaling. It serves as a valuable research tool for investigating TNFα-driven pathologies, including rheumatoid arthritis, in both cellular and animal model studies.
Product Specifications
CAS Number
2074702-04-6
Product Name Alternative
TNFαIN2, TNF-α-IN-2, TNFα-IN-2, TNF α IN 2, TNF-alpha-IN-2, TNF-a-IN-2
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.92% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (6.67 mM) ; DMSO:80 mg/mL (161.64 mM)
Smiles
N ([C@H] (C) C1=CC (C#N) =CC=C1F) C=2C3=C (C=C (F) C (=N3) C=4C=NC (C (C) (C) O) =NC4) N=C (C) C2Cl
Molecular Formula
C25H21ClF2N6O
Molecular Weight
494.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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