TMP-153
TMP-153 is a potent ACAT inhibitor with IC50 values of 5-10 nM against intestinal and hepatic enzymes. It demonstrates hypocholesterolemic activity by inhibiting cholesterol absorption, effectively lowering plasma cholesterol levels in rodent models such as rats and hamsters.
Product Specifications
CAS Number
128831-46-9
Product Name Alternative
ACAT, TMP153, TMP-153, TMP 153
Field of Research
Metabolism Research
Purity
99.61% (May vary between batches)
Solubility
DMF:10 mg/mL (22.84 mM) ; DMSO:30 mg/mL (68.51 mM)
Smiles
O=C (NC1=CC=C (F) C=C1F) NC2=CN=C3C=C (C (=CC3=C2C=4C=CC=CC4Cl) C) C
Molecular Formula
C24H18ClF2N3O
Molecular Weight
437.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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