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TMP-153

TMP-153 is a potent ACAT inhibitor with IC50 values of 5-10 nM against intestinal and hepatic enzymes. It demonstrates hypocholesterolemic activity by inhibiting cholesterol absorption, effectively lowering plasma cholesterol levels in rodent models such as rats and hamsters.

Product Specifications

CAS Number

128831-46-9

Product Name Alternative

ACAT, TMP153, TMP-153, TMP 153

Field of Research

Metabolism Research

Purity

99.61% (May vary between batches)

Solubility

DMF:10 mg/mL (22.84 mM) ; DMSO:30 mg/mL (68.51 mM)

Smiles

O=C (NC1=CC=C (F) C=C1F) NC2=CN=C3C=C (C (=CC3=C2C=4C=CC=CC4Cl) C) C

Molecular Formula

C24H18ClF2N3O

Molecular Weight

437.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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