CAY10746
CAY10746 is a potent and selective ROCK inhibitor, demonstrating IC50 values of 0.003 μM for ROCK II and 0.014 μM for ROCK I. Its application extends to research on diabetic retinopathy, including studies on vascular permeability and endothelial cell function in both cellular and animal models of the disease.
Product Specifications
CAS Number
2247240-76-0
Product Name Alternative
CAY10746, CAY-10746, CAY 10746, ROCK2, ROCK1
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.37 mM) ; DMSO:40 mg/mL (87.44 mM)
Smiles
CN (C) c1ccc (cc1) C (=O) Nc1cccc (NC (=O) COc2ccc3c (c2) occc3=O) c1
Molecular Formula
C26H23N3O5
Molecular Weight
457.48
Storage Conditions
-20°C
Notes
For research use only.
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