2-oxo Clopidogrel
2-oxo Clopidogrel ((±) -SR-121683) is a key thiolactone metabolite generated by CYP3A-mediated hepatic oxidation of the prodrug Clopidogrel. This intermediate is crucial for research into the metabolic activation pathway and can be hydrolyzed to form the active metabolite (CAM) in vitro, supporting pharmacological and pharmacokinetic studies.
Product Specifications
CAS Number
109904-27-0
Product Name Alternative
2oxo Clopidogrel, 2-oxo Clopidogrel, 2 oxo Clopidogrel, (±) -2-Oxo clopidogrel, (±) -SR-121683
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Solubility
DMF:PBS (pH 7.2) (1:20) :< 1 mg/mL, insoluble; Ethanol:5 mg/mL (14.8 mM) ; DMSO:200 mg/mL (592.03 mM) ; DMF:10 mg/mL (29.6 mM)
Smiles
O=C1SC2C (=C1) CN (CC2) C (C (=O) OC) C=3C=CC=CC3Cl
Molecular Formula
C16H16ClNO3S
Molecular Weight
337.82
Storage Conditions
-20°C
Notes
For research use only.
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