(S, R, S) -AHPC-PEG3-propionic acid
This functionalized VHL ligand is a key building block for PROTAC development, featuring an E3 ligase binder and a PEG linker for attaching a target protein ligand. It serves as a critical tool molecule for constructing heterobifunctional degraders, enabling targeted protein degradation research in both cellular and biochemical assays.
Product Specifications
CAS Number
2140807-42-5
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
C ([C@@H] (NC (CCOCCOCCOCCC (O) =O) =O) [C@@] (C) (C) C) (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1
Molecular Formula
C32H46N4O9S
Molecular Weight
662.79
Storage Conditions
-20°C
Notes
For research use only.
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