Thalidomide 4'-oxyacetamide-alkylC8-amine

This functionalized cereblon ligand is a key building block for PROTAC synthesis, featuring an E3 ligase binder connected via an alkylC8 linker to a terminal amine for conjugation. It is widely used in both in vitro and in vivo research to develop heterobifunctional degraders for targeted protein elimination in oncology and disease biology.