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VH 032 amide-alkylC2-acid

This functionalized VHL ligand is a key building block for PROTAC synthesis, featuring an E3 ligase-recruiting moiety and a carboxylic acid-terminated linker for conjugation. It is widely used in both in vitro and in vivo studies to develop heterobifunctional degraders for targeted protein degradation research.

Product Specifications

CAS Number

2172819-72-4

Smiles

Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) CCC (O) =O) C (C) (C) C) cc1

Molecular Formula

C26H34N4O6S

Molecular Weight

530.64

Storage Conditions

-20°C

Notes

For research use only.

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