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VH 032 amide-alkylC8-acid

This functionalized VHL ligand is a key building block for constructing PROTAC degraders, featuring an E3 ligase binder and a C8 linker with a terminal carboxylic acid for conjugation. It is widely used in both in vitro and in vivo studies to develop novel protein degraders targeting disease-relevant proteins for research purposes.

Product Specifications

CAS Number

2172819-77-9

Field of Research

Pharmacology & Drug Discovery

Smiles

Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) CCCCCCCCC (O) =O) C (C) (C) C) cc1 |@@:37|

Molecular Formula

C32H46N4O6S

Molecular Weight

614.8

Storage Conditions

-20°C

Notes

For research use only.

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