VH 032 amide-PEG1-acid
This functionalized VHL ligand is a key building block for PROTAC synthesis, featuring an E3 ligase binder connected via a PEG1 linker to a carboxylic acid for target warhead conjugation. It is widely used in both cellular and in vitro assays to develop degraders for cancer and disease-related proteins.
Product Specifications
CAS Number
2172820-07-2
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) CCOCCC (O) =O) C (C) (C) C) cc1 |@:34|
Molecular Formula
C28H38N4O7S
Molecular Weight
574.69
Storage Conditions
-20°C
Notes
For research use only.
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