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VH 032 amide-PEG1-acid

This functionalized VHL ligand is a key building block for PROTAC synthesis, featuring an E3 ligase binder connected via a PEG1 linker to a carboxylic acid for target warhead conjugation. It is widely used in both cellular and in vitro assays to develop degraders for cancer and disease-related proteins.

Product Specifications

CAS Number

2172820-07-2

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Smiles

Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) CCOCCC (O) =O) C (C) (C) C) cc1 |@:34|

Molecular Formula

C28H38N4O7S

Molecular Weight

574.69

Storage Conditions

-20°C

Notes

For research use only.

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