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MTOR inhibitor WYE-28

Compound 28 (WYE-28) is a potent and selective mTOR inhibitor with an IC50 of 0.08 nM, demonstrating secondary activity against PI3Kα (IC50=6 nM) . This small molecule is a valuable research tool for studying mTOR and PI3K signaling pathways in cancer biology, applicable in both cellular and biochemical assays.

Product Specifications

CAS Number

1062172-60-4

Field of Research

Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Purity

98.13% (May vary between batches)

Smiles

O=C (OC) N1CCC (N2N=CC=3C2=NC (=NC3N4CCOCC4) C=5C=CC (=CC5) NC (=O) NC6=CC=C (C=C6) CO) CC1

Molecular Formula

C30H34N8O5

Molecular Weight

586.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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