SM-1295
SM-1295 is a small molecule IAP antagonist with high affinity for c-IAP1-BIR3 (Kd = 3.2 nM) and c-IAP2-BIR3 (Kd = 9.5 nM), and lower affinity for XIAP-BIR3. It is used in research to study apoptosis regulation and has been applied in both in vitro and in vivo models of cancer.
Product Specifications
CAS Number
1562375-46-5
Field of Research
Cell Biology
Smiles
[H][C@]12CC[C@H] (N1C (=O) [C@H] (CN (CC2) C (=O) Cc1ccccc1) NC (=O) [C@H] (C) NC) C (=O) NCc1ccc (Br) cc1
Molecular Formula
C29H36BrN5O4
Molecular Weight
598.53
Storage Conditions
-20°C
Notes
For research use only.
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