C6 Urea Ceramide
C6 urea ceramide is a neutral ceramidase inhibitor that elevates cellular ceramide levels, selectively inhibiting proliferation and inducing apoptosis and autophagy in colon cancer cells like HT-29 and HCT116. It promotes β-catenin degradation and demonstrates in vivo efficacy by reducing tumor growth in xenograft models, making it a valuable research tool for studying ceramide metabolism and cancer biology.
Product Specifications
CAS Number
486991-52-0
Field of Research
Cell Biology, Kidney & Urological Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
[C@@H] (NC (NCCCCCC) =O) ([C@@H] (/C=C/CCCCCCCCCCCCC) O) CO
Molecular Formula
C25H50N2O3
Molecular Weight
426.68
Storage Conditions
-20°C
Notes
For research use only.
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