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C6 Urea Ceramide

C6 urea ceramide is a neutral ceramidase inhibitor that elevates cellular ceramide levels, selectively inhibiting proliferation and inducing apoptosis and autophagy in colon cancer cells like HT-29 and HCT116. It promotes β-catenin degradation and demonstrates in vivo efficacy by reducing tumor growth in xenograft models, making it a valuable research tool for studying ceramide metabolism and cancer biology.

Product Specifications

CAS Number

486991-52-0

Field of Research

Cell Biology, Kidney & Urological Research, Signal Transduction, Stem Cell & Developmental Biology

Smiles

[C@@H] (NC (NCCCCCC) =O) ([C@@H] (/C=C/CCCCCCCCCCCCC) O) CO

Molecular Formula

C25H50N2O3

Molecular Weight

426.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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