C8 D-threo Ceramide (d18:1/8:0)
C8 D-threo Ceramide is a cell-permeable, cytotoxic ceramide analog that potently induces DNA fragmentation and activates ceramide-activated protein kinase (CAPK) in U937 cells. It serves as a substrate for E. coli diacylglycerol kinase and enhances pore formation by V. cholerae cytolysin in lipid membrane models, supporting research in sphingolipid signaling, apoptosis, and bacterial toxin mechanisms.
Product Specifications
CAS Number
175892-43-0
Field of Research
Cell Biology
Smiles
CCCCCCCCCCCCC\C=C\[C@@H] (O) [C@@H] (CO) NC (=O) CCCCCCC
Molecular Formula
C26H51NO3
Molecular Weight
425.698
Storage Conditions
-20°C
Notes
For research use only.
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