Dios-Arg (trifluoroacetate salt)

Dios-Arg is a cationic steroid lipid featuring a diosgenin scaffold and an L-arginine headgroup, designed for nucleic acid delivery. It effectively complexes with and transfects plasmid DNA and siRNA into mammalian cells via lipid raft and caveolae-mediated endocytosis, useful for in vitro gene function studies. Its application in forming lipid nanoparticles supports research in gene therapy and molecular biology.