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GS-441524 tris-isobutyryl ester

GS-441524 tris-isobutyryl ester is a prodrug of the remdesivir metabolite GS-441524. It demonstrates antiviral activity against respiratory syncytial virus (RSV) in vitro, exhibiting an EC50 of 0.26 μM in reducing RSV-induced cytopathic effect in HEp-2 cells. This compound serves as a research tool for studying antiviral mechanisms and nucleoside analog prodrug strategies.

Product Specifications

CAS Number

2563617-99-0

Field of Research

Infectious Disease & Virology, Signal Transduction

Smiles

CC (C) C (=O) OC[C@H]1O[C@@] (C#N) ([C@H] (OC (=O) C (C) C) [C@@H]1OC (=O) C (C) C) c1ccc2c (N) ncnn12

Molecular Formula

C24H31N5O7

Molecular Weight

501.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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