Caylin-1
Caylin-1 is a chlorinated analog of the p53-MDM2 interaction inhibitor Nutlin-3. While less potent in growth inhibition at high doses, it exhibits a unique biphasic effect by promoting HCT116 cell proliferation at low concentrations. This compound is a valuable research tool for studying p53 pathway dynamics and context-dependent cell fate decisions in vitro.
Product Specifications
CAS Number
1207480-88-3
Field of Research
Pharmacology & Drug Discovery
Smiles
C (=O) (N1[C@H] ([C@H] (N=C1C2=C (OC (C) C) C=C (OC) C=C2) C3=CC (Cl) =C (Cl) C=C3) C4=CC (Cl) =C (Cl) C=C4) N5CC (=O) NCC5
Molecular Formula
C30H28Cl4N4O4
Molecular Weight
650.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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