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Benpyrine

Benpyrine is a potent, orally bioavailable small molecule that selectively inhibits TNF-α with a KD of 82.1 μM and an IC50 of 0.109 μM against the TNF-α/TNFR1 interaction. It serves as a valuable research tool for studying TNF-α-mediated pathways in inflammatory and autoimmune diseases, applicable in both cellular and animal model systems.

Product Specifications

CAS Number

2550398-89-3

Field of Research

Cell Biology

Smiles

O=C1C[C@@H] (CN1Cc1ccccc1) Nc1ncnc2[nH]cnc12

Molecular Formula

C16H16N6O

Molecular Weight

308.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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