CMLD-2
CMLD-2 is a potent, cell-permeable inhibitor of the HuR-ARE interaction (Ki: 350 nM) . It disrupts HuR's mRNA-stabilizing function, leading to downregulation of oncogenic targets like MAD2, which induces apoptosis, cell cycle arrest, and inhibits proliferation and migration in various cancer cell lines in vitro.
Product Specifications
CAS Number
958843-91-9
Product Name Alternative
CMLD 2, CMLD2, CMLD-2, Apoptosis
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
99.16% (May vary between batches)
Solubility
DMSO:65 mg/mL (126.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.89 mM)
Smiles
COc1ccc (cc1) C (CC (=O) N1CCCC1) c1c (OC) cc (OC) c2c (cc (=O) oc12) -c1ccccc1
Molecular Formula
C31H31NO6
Molecular Weight
513.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR207181L3V 200 µL
Tubb3 (NM_023279) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details GTR15261322 1 Vial
Lentiviral mouse Aldh1a7 shRNA (UAS) - Lentiviral mouse Aldh1a7 shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details GTR15123281 1 Vial
Lentiviral mouse Rmnd5a shRNA (UAS) - Lentiviral mouse Rmnd5a shRNA (UAS) (25)
Sign In for Pricing
View Details 
GTR10346289 96 Well
Guinea Pig amyloid beta peptide 25-35 (Aβ25-35) ELISA Kit
Sign In for Pricing
View Details 