IKK2-IN-4
IKK2-IN-4 (IKK2 Inhibitor VI) is a potent and selective IKK-2 inhibitor with an IC50 of 25 nM. It effectively suppresses LPS-induced TNF-α production in PBMCs, making it a valuable tool for studying NF-κB signaling in inflammatory and autoimmune disease research, both in vitro and in vivo.
Product Specifications
CAS Number
354811-10-2
Product Name Alternative
5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide, IKK2 Inhibitor IV, IKK2-IN-4, IKK2, IKK, IkB, IkB/IKK, IκB, TNF-α
Field of Research
Cell Biology, Signal Transduction
Purity
99.83% (May vary between batches)
Solubility
Ethanol:2 mg/mL (7.65 mM) ; DMSO:30 mg/mL (114.81 mM)
Smiles
N (C (N) =O) C=1SC (=CC1C (N) =O) C2=CC=CC=C2
Molecular Formula
C12H11N3O2S
Molecular Weight
261.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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