SDZ 224-015
SDZ 224-015 is a potent, orally bioavailable inhibitor of the IL-1β converting enzyme (caspase-1) . It demonstrates anti-inflammatory and anti-COVID-19 activity in research, validated by its efficacy in reducing carrageenan-induced paw edema in rat models and its use in cytokine storm-related in vitro studies.
Product Specifications
CAS Number
161511-45-1
Product Name Alternative
Caspase-1, IL Receptor, ILReceptor, IL-1β converting enzyme, SDZ 224-015, SDZ 224 015, SDZ 224015
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry
Purity
95.49% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (5.06 mM) ; DMSO:80 mg/mL (122.6 mM)
Smiles
CCOC (=O) C[C@H] (NC (=O) [C@H] (C) NC (=O) [C@@H] (NC (=O) OCc1ccccc1) C (C) C) C (=O) COC (=O) c1c (Cl) cccc1Cl
Molecular Formula
C30H35Cl2N3O9
Molecular Weight
652.52
Storage Conditions
-20°C
Notes
For research use only.
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