Quazinone
Quazinone is a selective PDE3 inhibitor exhibiting positive inotropic and vasodilatory effects. It relaxes human cavernosal smooth muscle in vitro and enhances cardiac contractility while lowering blood pressure in canine models. Furthermore, it concentration-dependently inhibits PDGF-BB-induced DNA synthesis in vascular smooth muscle cells.
Product Specifications
CAS Number
70018-51-8
Field of Research
Metabolism Research, Signal Transduction
Smiles
C[C@H]1N2C (NC=3C (C2) =C (Cl) C=CC3) =NC1=O
Molecular Formula
C11H10ClN3O
Molecular Weight
235.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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