PKI-402

PKI-402 is a highly potent dual inhibitor of PI3K and mTOR, demonstrating low nanomolar IC50 values against key isoforms including PI3Kα (2 nM) and mTOR (3 nM) . It is a valuable research tool for investigating the PI3K/Akt/mTOR signaling pathway in cancer and other diseases, with utility in both in vitro and in vivo experimental models.