PKI-402
PKI-402 is a highly potent dual inhibitor of PI3K and mTOR, demonstrating low nanomolar IC50 values against key isoforms including PI3Kα (2 nM) and mTOR (3 nM) . It is a valuable research tool for investigating the PI3K/Akt/mTOR signaling pathway in cancer and other diseases, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1173204-81-3
Product Name Alternative
PKI402, PKI-402, PKI 402
Field of Research
Signal Transduction
Purity
99.78% (May vary between batches)
Solubility
DMSO:5 mg/mL (8.76 mM)
Smiles
CCn1nnc2c (nc (nc12) -c1ccc (NC (=O) Nc2ccc (cc2) C (=O) N2CCN (C) CC2) cc1) N1CCOCC1
Molecular Formula
C29H34N10O3
Molecular Weight
570.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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