PKI-402
PKI-402 is a highly potent dual inhibitor of PI3K and mTOR, demonstrating low nanomolar IC50 values against key isoforms including PI3Kα (2 nM) and mTOR (3 nM) . It is a valuable research tool for investigating the PI3K/Akt/mTOR signaling pathway in cancer and other diseases, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1173204-81-3
Product Name Alternative
PKI402, PKI-402, PKI 402
Field of Research
Signal Transduction
Purity
99.78% (May vary between batches)
Solubility
DMSO:5 mg/mL (8.76 mM)
Smiles
CCn1nnc2c (nc (nc12) -c1ccc (NC (=O) Nc2ccc (cc2) C (=O) N2CCN (C) CC2) cc1) N1CCOCC1
Molecular Formula
C29H34N10O3
Molecular Weight
570.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb1975438 100 µL
Phospho-SHC1 (Tyr427) Rabbit Polyclonal Antibody (APC-Cy7)
Sign In for Pricing
View Details 
041358-ML490 100 µL
S100B, ID (S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B) (MaxLight 490) discontinued
Sign In for Pricing
View Details