(3S) -hydroxy Quinidine
(3S) -Hydroxy Quinidine is the major active metabolite of the antiarrhythmic drug Quinidine, formed primarily via CYP3A4 metabolism. This metabolite exhibits dose-dependent antiarrhythmic activity, effectively prolonging repolarization in canine Purkinje fibers in vitro and suppressing ventricular arrhythmias in isolated rat heart models post-reperfusion.
Product Specifications
CAS Number
53467-23-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
[C@H] (O) (C=1C2=C (C=CC (OC) =C2) N=CC1) [C@@]3 ([N@@]4C[C@@] (C=C) (O) [C@] (C3) (CC4) [H]) [H]
Molecular Formula
C20H24N2O3
Molecular Weight
340.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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