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(3S) -hydroxy Quinidine

(3S) -Hydroxy Quinidine is the major active metabolite of the antiarrhythmic drug Quinidine, formed primarily via CYP3A4 metabolism. This metabolite exhibits dose-dependent antiarrhythmic activity, effectively prolonging repolarization in canine Purkinje fibers in vitro and suppressing ventricular arrhythmias in isolated rat heart models post-reperfusion.

Product Specifications

CAS Number

53467-23-5

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

[C@H] (O) (C=1C2=C (C=CC (OC) =C2) N=CC1) [C@@]3 ([N@@]4C[C@@] (C=C) (O) [C@] (C3) (CC4) [H]) [H]

Molecular Formula

C20H24N2O3

Molecular Weight

340.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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