(E) -Guggulsterone
(E) -Guggulsterone is a stereoisomer of guggulsterone that acts as an FXR antagonist. It has demonstrated lipid-lowering effects, induces heme oxygenase-1, and exhibits antiviral activity by blocking dengue virus (DENV) NS2B/3B protease and replication in vitro.
Product Specifications
CAS Number
39025-24-6
Product Name Alternative
(E) Guggulsterone, (E) Guggulsterone, (-) - (E) -Guggulsterone, Guggulsterone
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research
Purity
99.94% (May vary between batches)
Solubility
Ethanol:1 mg/mL (3.2 mM) ; DMSO:20 mg/mL (64.01 mM) ; DMF:10 mg/mL (32.01 mM) ; DMF:PBS (pH 7.2) (1:4) :0.2 mg/mL (0.64 mM)
Smiles
[H][C@@]12CC (=O) \C (=C\C) [C@@]1 (C) CC[C@@]1 ([H]) [C@@]2 ([H]) CCC2=CC (=O) CC[C@]12C
Molecular Formula
C21H28O2
Molecular Weight
312.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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