HDAC3 Inhibitor
This potent and selective allosteric HDAC3 inhibitor exhibits a Ki of 0.16 nM and demonstrates significant selectivity in both enzymatic and cellular assays. It shows preferential activity against acute myeloid and monocytic leukemia cell lines, making it a valuable chemical probe for epigenetic research in oncology, particularly for studying HDAC3-specific roles in hematological malignancies.
Product Specifications
CAS Number
2044701-99-5
Field of Research
Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Smiles
C (NNCCC) (=O) C1=CC=C (CNC (/C=C/C2=CC=CC=C2) =O) C=C1
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
Storage Conditions
-20°C
Notes
For research use only.
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