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HDAC3 Inhibitor

This potent and selective allosteric HDAC3 inhibitor exhibits a Ki of 0.16 nM and demonstrates significant selectivity in both enzymatic and cellular assays. It shows preferential activity against acute myeloid and monocytic leukemia cell lines, making it a valuable chemical probe for epigenetic research in oncology, particularly for studying HDAC3-specific roles in hematological malignancies.

Product Specifications

CAS Number

2044701-99-5

Field of Research

Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Smiles

C (NNCCC) (=O) C1=CC=C (CNC (/C=C/C2=CC=CC=C2) =O) C=C1

Molecular Formula

C20H23N3O2

Molecular Weight

337.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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