PKI-166 hydrochloride
This orally bioavailable, potent, and selective EGFR kinase inhibitor (IC50 = 0.7 nM) demonstrates significant anti-metastatic and anti-angiogenic activity in pancreatic cancer mouse models. It is a valuable research tool for studying EGFR-driven oncology, with applications in both in vitro biochemical assays and in vivo preclinical research.
Product Specifications
CAS Number
2230253-82-2
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
Cl.C[C@@H] (Nc1ncnc2[nH]c (cc12) -c1ccc (O) cc1) c1ccccc1
Molecular Formula
C20H19ClN4O
Molecular Weight
366.85
Storage Conditions
-20°C
Notes
For research use only.
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