Tucatinib hemiethanolate
Tucatinib hemiethanolate (Irbinitinib hemiethanolate) is a potent, selective, and orally bioavailable HER2 tyrosine kinase inhibitor. It is utilized in preclinical and clinical research for metastatic HER2-positive cancers, including breast and colorectal cancer, demonstrating activity in both in vitro assays and in vivo models.
Product Specifications
CAS Number
1429755-56-5
Product Name Alternative
ARRY-380 hemiethanolate, HER2, ONT-380 hemiethanolate, Irbinitinib hemiethanolate, Tucatinib
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.76% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.28 mM) ; DMSO:125 mg/mL (124.12 mM)
Smiles
CCO.Cc1cc (Nc2ncnc3ccc (NC4=NC (C) (C) CO4) cc23) ccc1Oc1ccn2ncnc2c1.Cc1cc (Nc2ncnc3ccc (NC4=NC (C) (C) CO4) cc23) ccc1Oc1ccn2ncnc2c1
Molecular Formula
C54H54N16O5
Molecular Weight
1007.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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