Dehydro Nifedipine
Dehydro Nifedipine (BAY-b 4759) is the primary human plasma metabolite of the calcium channel blocker nifedipine, formed via CYP3A4/5 metabolism. This bioactive metabolite inhibits glucose uptake in PC-12 cells (IC50 = 130 μM), making it a relevant compound for research in metabolic studies and drug interaction mechanisms.
Product Specifications
CAS Number
67035-22-7
Product Name Alternative
DrugMetabolite, Drug Metabolite, Dehydro Nifedipine, BAY-b 4759, calcium channel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.65% (May vary between batches)
Solubility
DMSO:PBS (pH 7.2) (1:10) :0.1 mg/mL (0.29 mM) ; Ethanol:2.7 mg/mL (7.84 mM) ; DMSO:27 mg/mL (78.42 mM) ; DMF:30 mg/mL (87.13 mM)
Smiles
COC (=O) c1c (C) nc (C) c (C (=O) OC) c1-c1ccccc1[N+] ([O-]) =O
Molecular Formula
C17H16N2O6
Molecular Weight
344.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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