CAY10561
CAY10561 is a potent and selective ATP-competitive inhibitor of ERK2 (Ki=2 nM), a key kinase in the MAPK pathway constitutively active in many cancers. It inhibits proliferation in cellular models like COLO 205 cells (IC50=0.54 μM) and is a valuable tool for studying ERK-driven processes in oncology research.
Product Specifications
CAS Number
933786-58-4
Field of Research
Signal Transduction
Smiles
C (NC (CO) C1=CC (Cl) =C (F) C=C1) (=O) C2=CC (C=3C (=CNN3) C4=CC (Cl) =CC=C4) =CN2
Molecular Formula
C22H17Cl2FN4O2
Molecular Weight
459.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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