CAY10760
CAY10760 is a small molecule inhibitor that disrupts the RAD51-BRCA2 interaction, impairing homologous recombination. It reduces proliferation in pancreatic cancer cell lines, both alone and in combination with PARP inhibitors like olaparib, supporting its research use in studying DNA repair mechanisms and synthetic lethality.
Product Specifications
CAS Number
391889-85-3
Field of Research
Cell Biology, Molecular Biology
Smiles
O=C1NC=2C=CC (Cl) =CC2C (C=3C=CC=CC3) =C1C4=NN (C (=O) CC) C (C5=CC=C (OC) C=C5) C4
Molecular Formula
C28H24ClN3O3
Molecular Weight
485.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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