FM19G11
FM19G11 is a potent small molecule inhibitor of hypoxia-inducible factor (HIF) α-subunit, demonstrating an IC50 of 80 nM in a hypoxia-induced luciferase assay. It is a valuable research tool for studying HIF-mediated pathways in oncology and ischemia, applicable in both cellular and animal models of hypoxia.
Product Specifications
CAS Number
329932-55-0
Product Name Alternative
HIF-1a/2a Inhibitor, HIF-1α/2α Inhibitor, HIF-1α, HIF-1alpha/2alpha Inhibitor, FM19G11
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research
Purity
97.28% (May vary between batches)
Solubility
DMSO:90 mg/mL (194.22 mM)
Smiles
Cc1ccc (cc1) C (=O) COC (=O) c1cccc (NC (=O) c2ccc (cc2[N+] ([O-]) =O) [N+] ([O-]) =O) c1
Molecular Formula
C23H17N3O8
Molecular Weight
463.4
Storage Conditions
-20°C
Notes
For research use only.
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