Tetrac
Tetrac is a thyroid hormone derivative that acts as an antagonist at the cell-surface integrin αvβ3 receptor, blocking pro-angiogenic and proliferative signals from T4, T3, and EGFR. This mechanism underpins its studied anti-tumor and pro-apoptotic activities in colorectal cancer models, supporting its use in oncology and angiogenesis research.
Product Specifications
CAS Number
67-30-1
Product Name Alternative
Apoptosis, 3,3',5,5'-Tetraiodothyroacetic acid, EGFR, Tetrac, Tetraiodothyroacetic acid, thyroxine
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction
Purity
99.00% (May vary between batches)
Solubility
DMSO:45 mg/mL (60.17 mM)
Smiles
OC (=O) Cc1cc (I) c (Oc2cc (I) c (O) c (I) c2) c (I) c1
Molecular Formula
C14H8I4O4
Molecular Weight
747.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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