RO0270608
RO0270608 is the orally active metabolite of R411 and functions as a dual antagonist of α4β1 and α4β7 integrins. This anti-inflammatory compound is utilized in research to investigate allergic responses through modulation of leukocyte adhesion and migration in both cellular and animal models of inflammation.
Product Specifications
CAS Number
220846-33-3
Product Name Alternative
α4β1 integrin, α4β7 integrin, RO 0270608, RO0270608, RO-0270608
Field of Research
Signal Transduction
Purity
98.26% (May vary between batches)
Solubility
DMSO:8 mg/mL (15.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.98 mM)
Smiles
Cc1cccc (Cl) c1C (=O) N[C@@H] (Cc1ccc (NC (=O) c2c (Cl) cccc2Cl) cc1) C (O) =O
Molecular Formula
C24H19Cl3N2O4
Molecular Weight
505.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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