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BPIQ-II (hydrochloride)

BPIQ-II is a potent and highly selective linear imidazoloquinazoline inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 8 pM) . It acts as a competitive ATP-site binder, effectively blocking EGF-stimulated signaling in cellular assays, making it a valuable tool for cancer research and studying EGFR-driven pathways in vitro.

Product Specifications

CAS Number

171179-37-6

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

Cl.BrC1=CC=CC (=C1) NC2=NC=NC3=CC=4N=CNC4C=C32

Molecular Formula

C15H11BrClN5

Molecular Weight

376.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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