SW2_110A
SW2_110A is a cell-permeable, selective inhibitor of the chromodomain of CBX8 with a Kd of 800 nM, demonstrating 5-fold selectivity over other CBX family members. This small molecule is a valuable chemical probe for investigating Polycomb repressive complex 1 (PRC1) function in epigenetic regulation, cancer biology, and stem cell research in both cellular and biochemical assays.
Product Specifications
CAS Number
2579696-95-8
Product Name Alternative
CBX8, HistoneMethyltransferase, Histone Methyltransferase, SW2_110A, SW-2_110A
Field of Research
Epigenetics & Chromatin
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.26 mM) ; DMSO:112.5 mg/mL (147.84 mM)
Smiles
[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC#C) =O) CO) =O) CCCCN (CC) CC) =O) [C@@H] (CC) C) =O) (NC (=O) C1=CC=C (OC2=CC=CC=C2) C=C1) [C@H]3CCCC3
Molecular Formula
C42H60N6O7
Molecular Weight
760.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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